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Doing cancer research openly, publishing data while searching for effective drugs.

Jay Bradner

In the post-genomic era, the discovery of cancer genes has become relatively straightforward.
Cancer biologists and geneticists now race, like modern cartographers, to assimilate this information
as a unified geography of cell signaling pathways. For the cancer patient, these advances allow a detailed,
highly individualized understanding of cancer's hard-wiring. Unfortunately, the delay in the discovery
and delivery of targeted therapeutics remains a significant concern. We invoke a utilitarian model
of drug discovery which is not restricted by any individual chemistry or technology.
We support a collaborative, creative approach to drug discovery focused on the most pressing targets
irrespective of perceived 'druggability' or profitability. -- Lab research page excerpt.

Jay Bradner's TED lecture on open source cancer research. Selective inhibition of BET bromodomains

Directions to pursue, link dump

Not open research specific. To be sorted and moved to specific sections, or separate page.


  • bbc reporting on Riken / _ research published in journal Cell Stem Cell about cancer & HIV attacking T-cells. Not proven to differentiate. Early stage. Reported as promising.
    • Teams at the University of Tokyo and the Riken Research Centre for Allergy and Immunology used advances in stem cell technology to make more T-cells.

Unsorted Labs